ICMR to launch study to evaluate efficacy of BCG vaccine against coronavirus COVID-19 in elderly
Amid the rising coronavirus COVID-19 circumstances within the nation, the India Council of Medical Research (ICMR) has determined to conduct a research to judge the effectiveness of the BCG vaccination in stopping morbidity and mortality as a result of extremely contagious virus in aged people between 60 to 95 years of age. The ICMR groups will conduct the research on the folks residing in COVID-19 hotspots throughout the nation.
It is learnt that the ICRM will perform the research in Maharashtra, Tamil Nadu, Gujarat, Madhya Pradesh, Rajasthan, and Delhi.
The stidy might be lead by Chennai-based ICMR’s National Institute for Research in Tuberculosis (NIRT). In Chennai, the ICMR will conduct the research in collaboration with the Greater Chennai Corporation and Tamil Nadu’s Department of Public Health.
“The study will document whether BCG vaccine can prevent the occurrence of the SARS-CoV-2 infection and its progression and death associated with COVID-19 among elderly individuals. The study uses the same BCG vaccine that is administered to newborn babies as a part of National Immunization programme for more than 50 years in this country,” Dr Subash Babu, Scientific Director at National Institute of Research in Tuberculosis advised ANI.
“Based on the capacity of BCG to reduce the incidence of respiratory tract infections in children and adults, to exert antiviral effects in experimental models; and to reduce viremia in an experimental human model of viral infection, the hypothesis is that BCG vaccination will partially protect against mortality in high-risk, elderly individuals,” he added.
Babu additionally famous that a number of scientific trials utilizing BCG vaccine are alreayd beneath progress on aged people in several components of the world.
“We have to evaluate the effectiveness of BCG vaccination in terms of reduction in the cumulative incidence of hospital admission and Intensive Care Admission, reduction in the incidence of other respiratory febrile illness, to determine the innate and adaptive immune responses, IgM, IgG and IgA antibody titers generated by BCG vaccination (both total and SARS-Cov2 specific) in a subset of individuals and to measure biomarkers induced by BCG vaccination as correlates of risk or protection against SARS-Cov2 in a subset of individuals,” added Dr Babu.
Apart from Chennai’s NIRT website, the 5 different centres are National Institute of Occupational Health, Ahmedabad in Gujarat, National Institute for Research in Environmental Health in Bhopal in Madhya Pradesh, GS Medical College and KEM Hospital in Mumbai Maharashtra, National Institute for Implementation Research on Non-Communicable Diseases in Jodhpur and AIIMS, New Delhi.
$(function() { return $("[data-sticky_column]").stick_in_parent({ parent: "[data-sticky_parent]" }); });
reset_scroll = function() { var scroller; scroller = $("body,html"); scroller.stop(true); if ($(window).scrollTop() !== 0) { scroller.animate({ scrollTop: 0 }, "fast"); } return scroller; };
window.scroll_it = function() { var max; max = $(document).height() - $(window).height(); return reset_scroll().animate({ scrollTop: max }, max * 3).delay(100).animate({ scrollTop: 0 }, max * 3); };
window.scroll_it_wobble = function() { var max, third; max = $(document).height() - $(window).height(); third = Math.floor(max / 3); return reset_scroll().animate({ scrollTop: third * 2 }, max * 3).delay(100).animate({ scrollTop: third }, max * 3).delay(100).animate({ scrollTop: max }, max * 3).delay(100).animate({ scrollTop: 0 }, max * 3); };
$(window).on("resize", (function(_this) { return function(e) { return $(document.body).trigger("sticky_kit:recalc"); }; })(this));
}).call(this);
} on_load_google_ad(); function sendAdserverRequest() { try { if (pbjs && pbjs.adserverRequestSent) return; googletag.cmd.push(function() { googletag.pubads().refresh(); }); } catch (e) {
googletag.cmd.push(function() { googletag.pubads().refresh(); }); } } setTimeout(function() { sendAdserverRequest(); }, 5000);
function on_load_fb_twitter_widgets(){ (function(d, s, id) { var js, fjs = d.getElementsByTagName(s)[0]; if (d.getElementById(id)) return; js = d.createElement(s); js.id = id; js.src = "https://connect.facebook.net/en_US/sdk.js#xfbml=1&version=v2.9"; fjs.parentNode.insertBefore(js, fjs); }(document, 'script', 'facebook-jssdk'));
window.twttr = (function(d, s, id) { var js, fjs = d.getElementsByTagName(s)[0], t = window.twttr || {}; if (d.getElementById(id)) return t; js = d.createElement(s); js.id = id; js.src = "https://platform.twitter.com/widgets.js"; fjs.parentNode.insertBefore(js, fjs); t._e = []; t.ready = function(f) {
t._e.push(f); }; return t; }(document, "script", "twitter-wjs")); }
//setTimeout(function() { on_load_google_ad(); }, 5000); setTimeout(function() { on_load_fb_twitter_widgets(); }, 5000);
Source